Cefixime’s efficacy varies depending on the specific bacteria causing the UTI. It’s highly active against Escherichia coli (E. coli), a common UTI culprit. Studies show high susceptibility rates, often exceeding 90%, in many geographical areas. However, resistance is emerging, so local susceptibility patterns should guide treatment decisions.
Klebsiella pneumoniae, another frequent UTI pathogen, also demonstrates susceptibility to cefixime in many cases, but again, resistance is a growing concern. Therefore, culture and sensitivity testing is critical for optimal treatment.
Cefixime’s activity against Proteus mirabilis and Proteus vulgaris is generally good, but similar caveats about rising resistance apply. These bacteria are known for producing urease, complicating UTIs.
For Enterococcus species, cefixime is typically ineffective. Alternative antibiotics are necessary for these infections. Similarly, cefixime shows limited activity against Pseudomonas aeruginosa, another possible UTI pathogen.
Always consult with a healthcare professional to determine the appropriate antibiotic for your specific UTI. They will consider your symptoms, medical history, and local antibiotic resistance patterns to choose the most suitable treatment. Self-treating UTIs can lead to complications and worsen the infection.
