Finasteride works by inhibiting the enzyme 5-alpha-reductase, specifically the type II isoenzyme. This enzyme converts testosterone to dihydrotestosterone (DHT), a potent androgen responsible for prostate growth and some aspects of male sexual characteristics. By reducing DHT levels, finasteride shrinks the prostate in men with benign prostatic hyperplasia (BPH).
However, this DHT reduction can impact sexual function. Lower DHT levels can lead to decreased libido, erectile dysfunction (ED), and ejaculatory disorders. The severity varies significantly between individuals. Some men experience no side effects, while others report noticeable changes.
The exact mechanism linking finasteride-induced DHT reduction and sexual dysfunction isn’t fully understood. It’s believed to involve complex interactions within the hypothalamus-pituitary-gonadal (HPG) axis, affecting hormone regulation and feedback loops.
Important Considerations: The risk of sexual side effects is generally considered low, but it’s crucial to discuss potential risks with your doctor before starting finasteride. They can help weigh the benefits against potential side effects based on your individual health profile. If sexual side effects occur, reporting them to your physician is vital. In many cases, these effects are temporary and resolve upon cessation of treatment. However, some individuals may experience persistent side effects.
Remember: This information is for educational purposes only and does not constitute medical advice. Consult your doctor for personalized guidance.
