Always inform your doctor about all medications you’re taking, including over-the-counter drugs, supplements, and herbal remedies, before starting Sildenafil. This is crucial for preventing potentially harmful interactions.
Nitrates and Sildenafil
Combining Sildenafil with nitrates, often found in medications for chest pain (angina), can cause a dangerous drop in blood pressure. This combination is strictly contraindicated. Avoid using Sildenafil if you are taking nitrate medications.
Alpha-Blockers and Sildenafil
Concomitant use of Sildenafil and alpha-blockers (used to treat high blood pressure or benign prostatic hyperplasia) can significantly lower blood pressure. Your doctor may adjust your dosage or recommend alternative treatments to mitigate this risk.
CYP3A4 Inhibitors and Sildenafil
Medications that inhibit the CYP3A4 enzyme (like ketoconazole, erythromycin, and ritonavir) can increase Sildenafil levels in your blood, potentially leading to increased side effects. Your doctor might lower your Sildenafil dose if you’re taking a CYP3A4 inhibitor.
Other Potential Interactions
Sildenafil can interact with other medications, including those for heart conditions, blood pressure, and HIV/AIDS. Open communication with your physician ensures safe and effective treatment.
