Penicillin remains the first-line treatment for Group B Streptococcus (GBS) infection in most cases. It’s generally well-tolerated and highly effective.
Ampicillin is another suitable alternative, offering a similar efficacy profile to penicillin. Consider ampicillin if a penicillin allergy exists, but always verify the allergy type with a physician before substituting.
For penicillin-allergic individuals with a non-immediate hypersensitivity reaction, cephalosporins like cefazolin provide a viable option. However, cross-reactivity with penicillin can occur, so careful assessment is necessary.
Clindamycin offers an alternative, particularly in cases of penicillin or cephalosporin resistance. However, resistance patterns vary geographically, so local antibiograms should guide treatment decisions.
Vancomycin is a last-resort antibiotic used only when resistance to other agents is confirmed. Its use is generally reserved for severe infections and should be guided by susceptibility testing.
Always consult with a healthcare professional to determine the most appropriate antibiotic based on individual patient factors, such as the severity of the infection, the presence of allergies, and local resistance patterns. This information should not replace professional medical advice.
