Finasteride lowers dihydrotestosterone (DHT) levels, a potent androgen significantly influencing sexual function. This reduction can lead to decreased libido, erectile dysfunction, and ejaculatory disorders in some men.
Mechanism: Finasteride inhibits the type II 5α-reductase enzyme, preventing testosterone’s conversion to DHT. Lower DHT directly impacts the prostate and hair follicles, the intended therapeutic effects, but also indirectly affects sexual function. The exact mechanisms linking DHT reduction and sexual side effects remain a subject of ongoing research.
Prevalence: Studies indicate that sexual side effects occur in approximately 2-5% of men using finasteride for benign prostatic hyperplasia (BPH) and a slightly higher percentage in those using it for male pattern baldness. However, these figures vary widely depending on study methodology and patient populations.
Individual Variation: Responses to finasteride are highly individual. Factors influencing the likelihood of sexual side effects include age, genetic predisposition, and pre-existing conditions. Some men experience no side effects at all.
Management: If sexual side effects occur, discontinuation of finasteride is often the first step. In some cases, symptoms may resolve upon cessation; however, for others, symptoms might persist for extended periods, even months or years. Consult a physician if you experience these adverse effects; they may suggest alternative treatments or strategies for managing the symptoms.
Important Note: This information is for educational purposes only and does not constitute medical advice. Always consult your doctor before starting or stopping any medication.
