Viagra, or sildenafil citrate, primarily targets a specific enzyme called phosphodiesterase-5 (PDE5). PDE5 breaks down a crucial messenger molecule, cyclic guanosine monophosphate (cGMP).
By inhibiting PDE5, Viagra allows cGMP to persist in the smooth muscles of blood vessels in the penis. Higher cGMP levels relax these muscles, increasing blood flow into the penis, leading to an erection.
This process is triggered by sexual stimulation. Viagra doesn’t automatically cause an erection; sexual stimulation is necessary to initiate the chain of events.
The effects of Viagra generally begin within 30-60 minutes and can last for up to 4 hours. The duration and intensity can vary depending on individual factors.
| Dosage | Higher doses generally lead to stronger and longer-lasting effects, but also increase the risk of side effects. |
| Food intake | High-fat meals can delay absorption and onset of action. |
| Age and health | Underlying health conditions can affect the response to Viagra. |
| Alcohol consumption | Excessive alcohol use may reduce Viagra’s effectiveness. |
It’s crucial to consult a doctor before using Viagra, as it can interact negatively with certain medications, including nitrates. Your doctor can assess your health and determine the appropriate dosage.
