Penegra, containing Sildenafil Citrate, primarily enhances erectile function by inhibiting phosphodiesterase-5 (PDE5). PDE5 is an enzyme that breaks down cyclic guanosine monophosphate (cGMP), a crucial molecule for achieving and maintaining an erection.
By blocking PDE5, Penegra allows cGMP levels to rise. Increased cGMP relaxes the smooth muscles in the penis, increasing blood flow into the corpora cavernosa. This increased blood flow creates the engorgement necessary for a firm erection.
The effect is triggered by sexual stimulation. Sexual stimulation releases nitric oxide, which in turn activates the cGMP pathway. Penegra’s action potentiates this natural process, making erections more likely and stronger.
Remember, Penegra works best in conjunction with sexual stimulation. It doesn’t directly cause an erection; it facilitates the natural erectile response.
