Clomid, or clomiphene citrate, works by blocking estrogen receptors in the hypothalamus. This blockage tricks your body into thinking estrogen levels are low, prompting the pituitary gland to release more follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Increased FSH stimulates multiple follicles to develop in your ovaries, increasing the chance of multiple eggs being released during ovulation. This increased follicle development is the primary reason Clomid increases the risk of Ovarian Hyperstimulation Syndrome (OHSS).
OHSS severity varies greatly. Mild OHSS might cause bloating and pelvic discomfort. Severe OHSS, however, presents a more serious health risk, potentially leading to abdominal pain, nausea, vomiting, shortness of breath, and even life-threatening complications requiring hospitalization.
Factors influencing OHSS risk include age, body mass index (BMI), and ovarian response to Clomid. Women with polycystic ovary syndrome (PCOS) have a higher risk than those without. Close monitoring through blood tests and ultrasound scans is vital to detect early signs of OHSS.
Your doctor will carefully adjust your Clomid dosage and monitor your response. They might use lower doses or cancel your cycle if they detect excessive ovarian stimulation. Open communication with your healthcare provider about any symptoms you experience is paramount.
Remember, while Clomid significantly increases pregnancy chances, it carries risks. Thorough understanding of these risks and proactive monitoring are vital for safe and successful treatment.
