Prednisone suppresses your immune system. It achieves this by decreasing the production of inflammatory substances like cytokines. These molecules are key players in your body’s immune response, responsible for inflammation and the recruitment of immune cells to fight infection.
Specifically, prednisone impacts various immune cells. It reduces the activity of lymphocytes, a type of white blood cell crucial for targeted immune responses. It also affects macrophages, cells that engulf and destroy pathogens. This overall reduction in immune cell activity lessens the body’s inflammatory reaction.
This immunosuppressive effect is why prednisone is effective in treating autoimmune diseases, where the immune system mistakenly attacks the body’s own tissues. However, this also makes you more susceptible to infections, including shingles.
Remember: Prednisone’s impact on the immune system varies depending on the dose and duration of treatment. High doses and prolonged use significantly weaken immune defenses.
Caution: If you’re taking prednisone, discuss any signs of infection with your doctor immediately. Prompt medical attention is crucial for managing infections while on this medication.
