Prednisone is a corticosteroid medication, a synthetic version of the hormone cortisol your body naturally produces. It powerfully reduces inflammation and suppresses your immune system.
How Prednisone Reduces Inflammation
Prednisone works by binding to receptors inside your cells. This triggers a cascade of events that ultimately decrease the production of inflammatory substances like prostaglandins and leukotrienes. This reduction in inflammation leads to symptom relief in conditions like allergies, asthma, and autoimmune diseases.
Prednisone’s Impact on the Immune System
The immune system suppression is a significant effect. Prednisone decreases the number and activity of several immune cells, including white blood cells (WBCs). This effect is why you might see an elevated WBC count *initially*, followed by a suppression during long-term use. The initial rise can be due to complex interactions within the immune system. This is something your doctor will monitor closely.
Understanding WBC Elevation with Prednisone
| Initial Phase | May be elevated | Complex immune system response; temporary. |
| Long-Term Use | Usually suppressed | Prednisone’s immunosuppressive effects dominate. |
Important Note:
Prednisone is a powerful medication with potential side effects. Always follow your doctor’s instructions carefully. Regular blood tests are vital to monitor your WBC count and other vital signs during treatment. Never adjust your dosage without consulting your physician.
